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True Aneurysms of the Posterior Communicating Artery: a Systematic review and Meta-Analysis of Individual Patient data.
World Neurosurg
  • Wenzhuan He, Lehigh Valley Health Network
  • Chirag D Gandhi
  • John Quinn
  • Reza Karimi
  • Charles J Prestigiacomo
Publication/Presentation Date
1-1-2011
Abstract
OBJECTIVE: To review and analyze systematically the reported cases of "true" posterior communicating artery (PCoA) aneurysm. METHODS: A retrospective review of the published literature was performed, and a meta-analysis of individual patient data was conducted. RESULTS: Pooled data showed that "true" PCoA aneurysms represent about 1.3% (95% confidence interval [CI] 0.8%, 1.7%) of all intracranial aneurysms and 6.8% (95% CI 4.3%, 9.2%) of all PCoA aneurysms. Mean patient age was 53.5 years (53.5 years ± 15.4), and age range was 23-79 years. Of the 49 patients reported in the literature, 44 (89.8%) were reported as ruptured, and 4 (10.2%) were reported as unruptured. There were no significant differences in ruptured status between age (P = 0.321), left vs right aneurysm (P = 0.537), and shape of aneurysm (P = 0.408). No significant differences in complication rates were found between rupture status (P = 0.27), and operative modalities (P = 0.878). The mean ages of patients who had no complications and patients who had complications were 53 years (53 years ± 2.59) vs 53.2 years (53.2 years ± 5.02) (P = 0.972). CONCLUSIONS: "True" PCoA aneurysms represent about 1.3% of all intracranial aneurysms and 6.8% of all PCoA aneurysms. They are more prone to rupture compared with their counterpart junctional aneurysms. When surgical management is indicated, a good understanding of the location and configuration of the aneurysm neck before surgical treatment is critical in the successful treatment of these lesions.
PubMedID
21492665
Document Type
Article
Citation Information

HE, W; et al. True aneurysms of the posterior communicating artery: a systematic review and meta-analysis of individual patient data. World Neurosurgery. United States, 75, 1, 64-72, Jan. 2011. ISSN: 1878-8769.