The asymptotic wave speed for FKPP type reaction-diffusion equations on a class of infinite random metric trees are considered. We show that a travelling wavefront emerges, provided that the reaction rate is large enough. The wavefront travels at a speed that can be quantified via a variational formula involving the random branching degrees d→ and the random branch lengths ℓ→ of the tree 𝕋d→,ℓ→. This speed is slower than that of the same equation on the real line R, and we estimate this slow down in terms of d→ and ℓ→. The key idea is to project the Brownian motion on the tree onto a one-dimensional axis along the direction of the wave propagation. The projected process is a multi-skewed Brownian motion, introduced by Ramirez [31], with skewness and interface sets that encode the metric structure (d→ , ℓ→) of the tree. Combined with analytic arguments based on the Feynman-Kac formula, this idea connects our analysis of the wavefront propagation to the large deviations principle (LDP) of the multi-skewed Brownian motion with random skewness and random interface set. Our LDP analysis involves delicate estimates for an infinite product of 2 x 2 random matrices parametrized by d→ and ℓ→ and for hitting times of a random walk in random environment.