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Single-component versus multicomponent dietary goals for the metabolic syndrome: a randomized trial
Preventive and Behavioral Medicine Publications and Presentations
  • Yunsheng Ma, University of Massachusetts Medical School
  • Barbara C. Olendzki, University of Massachusetts Medical School
  • Jinsong Wang, Medical College of Yangzhou University
  • Gioia M. Persuitte, University of Massachusetts Medical School
  • Wenjun Li, University of Massachusetts Medical School
  • Hua (Julia) Fang, University of Massachusetts Medical School
  • Philip A. Merriam, University of Massachusetts Medical School
  • Nicole M. Wedick, University of Massachusetts Medical School
  • Ira S. Ockene, University of Massachusetts Medical School
  • Annie L. Culver, University of Massachusetts Medical School
  • Kristin L. Schneider, Rosalind Franklin University of Medicine and Science
  • Gin-Fei Olendzki, University of Massachusetts Medical School
  • James Carmody, University of Massachusetts Medical School
  • Tingjian Ge, University of Massachusetts - Lowell
  • Zhiying Zhang, University of Massachusetts Medical School
  • Sherry L. Pagoto, University of Massachusetts Medical School
UMMS Affiliation
Department of Medicine, Division of Preventive and Behavioral Medicine; Department of Quantitative Health Science, Division of Biostatistics and Health Services Research; Department of Medicine, Division of Cardiovascular Medicine; UMass Worcester Prevention Research Center
Date
2-17-2015
Document Type
Article
Abstract
BACKGROUND: Few studies have compared diets to determine whether a program focused on 1 dietary change results in collateral effects on other untargeted healthy diet components. OBJECTIVE: To evaluate a diet focused on increased fiber consumption versus the multicomponent American Heart Association (AHA) dietary guidelines. DESIGN: Randomized, controlled trial from June 2009 to January 2014. (ClinicalTrials.gov: NCT00911885). SETTING: Worcester, Massachusetts. PARTICIPANTS: 240 adults with the metabolic syndrome. INTERVENTION: Participants engaged in individual and group sessions. MEASUREMENTS: Primary outcome was weight change at 12 months. RESULTS: At 12 months, mean change in weight was -2.1 kg (95% CI, -2.9 to -1.3 kg) in the high-fiber diet group versus -2.7 kg (CI, -3.5 to -2.0 kg) in the AHA diet group. The mean between-group difference was 0.6 kg (CI, -0.5 to 1.7 kg). During the trial, 12 (9.9%) and 15 (12.6%) participants dropped out of the high-fiber and AHA diet groups, respectively (P = 0.55). Eight participants developed diabetes (hemoglobin A1c level > /=6.5%) during the trial: 7 in the high-fiber diet group and 1 in the AHA diet group (P = 0.066). LIMITATIONS: Generalizability is unknown. Maintenance of weight loss after cessation of group sessions at 12 months was not assessed. Definitive conclusions cannot be made about dietary equivalence because the study was powered for superiority. CONCLUSION: The more complex AHA diet may result in up to 1.7 kg more weight loss; however, a simplified approach to weight reduction emphasizing only increased fiber intake may be a reasonable alternative for persons with difficulty adhering to more complicated diet regimens. PRIMARY FUNDING SOURCE: National Heart, Lung, and Blood Institute.
Comments

Citation: Ann Intern Med. 2015 Feb 17;162(4):248-57. doi: 10.7326/M14-0611. Link to article on publisher's site

Related Resources
Link to Article in PubMed
PubMed ID
25686165
Citation Information
Yunsheng Ma, Barbara C. Olendzki, Jinsong Wang, Gioia M. Persuitte, et al.. "Single-component versus multicomponent dietary goals for the metabolic syndrome: a randomized trial" Vol. 162 Iss. 4 (2015) ISSN: 0003-4819 (Linking)
Available at: http://works.bepress.com/wenjun_li/112/