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Article
Peptide ligation catalyzed by functionalized gold nanoparticles
Journal of the American Chemical Society
(2007)
Abstract
Trimethylammonium functionalized gold nanoparticles are demonstrated as templates for the assembly of peptide fragments and their subsequently promoted ligation. This system displays the use of organically tailored nanoparticles as effective supramolecular reagents for catalyzing bond-forming reactions and may also serve as a model for prebiotic conditions where charged surfaces may have promoted the polymerization of the early biopolymers.
Disciplines
Publication Date
May 9, 2007
Publisher Statement
DOI: 10.1021/ja070301+
Copyright © 2007 American Chemical Society
Citation Information
Y Fillon, A Verma, P Ghosh, D Ernenwein, et al.. "Peptide ligation catalyzed by functionalized gold nanoparticles" Journal of the American Chemical Society Vol. 129 Iss. 21 (2007) Available at: http://works.bepress.com/vincent_rotello/68/