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Contribution to Book
Heterochronic Genes
C. elegans II (1997)
  • Victor R. Ambros, Dartmouth College
This chapter focuses on our current understanding of the C. elegans heterochronic gene pathway as determined by genetic characterization of the regulatory interactions among the genes (Ambros and Horvitz 1987; Ambros 1989; Liu and Ambros 1989) and recent progress on the cloning, sequencing, and molecular analysis of genes involved in this pathway (Ruvkun et al. 1989; Arasu et al. 1991; Papp et al. 1991; Wightman et al. 1991; Lee et al. 1993; Rougvie and Ambros 1995; E. Moss et al., in prep). Primary emphasis is placed on the developmental decisions controlled by the heterochronic genes, the regulatory interactions among genes of the pathway, and the effects of lin-14 on the expression of cell fates throughout larval development.
Publication Date
Riddle DL, Blumenthal T, Meyer BJ, Priess JR
Cold Spring Harbor Laboratory Press
Citation Information
Victor R. Ambros. "Heterochronic Genes" 2ndCold Spring Harbor, NYC. elegans II (1997)
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