The aim of this work is to study the environment that affects and influences in the creation of regional patents. With this purpose the patenting process is modeled as dynamic one where, beside other factors, its past values contribute to create synergies to continue patenting in a feedback process. Using a dynamic panel data estimator we find that past patenting level trends to encourage the actual one. Also, a positive and significant effect of education, university expenditure, population density and industrial concentration on patents is reported in the Mexican states set. Conclusions highlight that agglomeration forces are the main factor for patenting, followed by university expenditure and industrial concentration.