Skip to main content
Other
Immunocontraception in male feral swine treated with a recombinant gonadotropin-releasing hormone vaccine
USDA National Wildlife Research Center - Staff Publications
  • Tyler A. Campbell, USDA-APHIS, NWRC, Kingsville, TX Field Station
  • Michelle R. Garcia, Texas A&M University-Kingsville
  • Lowell A. Miller, USDA NWRC, Fort Collins, CO
  • Martha A. Ramirez, Texas A&M University-Kingsville
  • David B. Long, USDA-APHIS, NWRC, Kingsville, TX Field Station
  • Jean-Baptiste Marchand, Imaxio SA, Lyon, France
  • Fergal Hill, Imaxio SA, Lyon, France
Date of this Version
6-1-2010
Comments
Published in Journal of Swine Health and Production - May and June 2010.
Abstract
Objective: To determine if a recombinant gonadotropin-releasing hormone (GnRH) vaccine is a potential immunocontraceptive agent for juvenile male feral swine. Results: As expected, a single dose of GonaCon vaccine reduced testes mass, serum testosterone, and percent normal tubules, and restricted sperm development at each stage. These reductions in reproductive development were associated with elevated GnRH antibodies. The single injection of rGnRH was not as effective in reducing these reproductive parameters; however, the two-dose injection of rGnRH was as effective as the single injection of GonaCon.
Citation Information
Tyler A. Campbell, Michelle R. Garcia, Lowell A. Miller, Martha A. Ramirez, et al.. "Immunocontraception in male feral swine treated with a recombinant gonadotropin-releasing hormone vaccine" (2010)
Available at: http://works.bepress.com/tyler_campbell/12/