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Presentation
A Comparison of Codon Usage Trends in Prokaryotes
Proceedings of the Ohio Collaborative Conference on Bioinformatics, 2009
  • Amanda L. Hanes, Wright State University - Main Campus
  • Michael L. Raymer, Wright State University - Main Campus
  • Travis E. Doom, Wright State University - Main Campus
  • Dan E. Krane, Wright State University - Main Campus
Document Type
Conference Proceeding
Publication Date
6-1-2009
Abstract
Codon usage bias is an effective measure of the differences among organisms at a genomic level. These genomic differences also reflect some differences in the organisms’ lifestyles and physiology. Here we demonstrate that prokaryotic obligate intracellular parasites and symbionts have a codon usage pattern that differs significantly from that of exclusively free-living prokaryotes. This result is valuable in that it suggests that the habitat of an organism may directly influence that organism’s use of synonymous codons, which in turn demonstrates evidence of an evolutionary mechanism that operates at a finer molecular level than that of amino acids and proteins.
Comments

Presented at the Ohio Collaborative Conference on Bioinformatics (OCCBIO), Cleveland, OH, June 15-17, 2009.

DOI
10.1109/OCCBIO.2009.26
Citation Information
Amanda L. Hanes, Michael L. Raymer, Travis E. Doom and Dan E. Krane. "A Comparison of Codon Usage Trends in Prokaryotes" Proceedings of the Ohio Collaborative Conference on Bioinformatics, 2009 (2009) p. 83 - 86 ISSN: 9780769536859
Available at: http://works.bepress.com/travis_doom/24/