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Article
Commentary on: Budowle B, Shea B, Niezgoda S, Chakraborty R. CODIS STR Loci Data from 41 Sample Populations. J. Forensic Sci 2001; 46:453-489
Journal of Forensic Sciences
  • Dan E. Krane, Wright State University - Main Campus
  • Travis E. Doom, Wright State University - Main Campus
  • L. Mueller
  • Michael L. Raymer, Wright State University - Main Campus
  • W. Shields
  • William C. Thompson
Document Type
Letter
Publication Date
11-1-2004
Catalog Record
Catalog Record
Abstract
In an article on allele frequencies for CODIS loci in 41 different populations, Budowle et al. (1) reported no significant deviations from Hardy-Weinberg expectations (HWE) after making theBonferroni correction for multiple tests. However, examination of the data reported in (1) for two Native American populations, Navaho and Salishan, shows significant departures from HWE at three loci for each population. Budowle et al. appear to have relied on an incorrect and unsupportable application of the Bonferroni correction (2,3) to disregard these deviations. These loci should not be used when the product rule is employed to compute the frequency of multi-locus genotypes in these populations unless appropriate corrective actions are taken to account for the observed deviations from HWE.
DOI
10.1520/JFS2004162
Citation Information
Dan E. Krane, Travis E. Doom, L. Mueller, Michael L. Raymer, et al.. "Commentary on: Budowle B, Shea B, Niezgoda S, Chakraborty R. CODIS STR Loci Data from 41 Sample Populations. J. Forensic Sci 2001; 46:453-489" Journal of Forensic Sciences Vol. 49 Iss. 6 (2004) ISSN: 00221198
Available at: http://works.bepress.com/travis_doom/10/