Integrative rehabilitation practice (IRP) aims to improve clinicians' ability to connect the dots between body-mind-environment (BME). Patients present as individuals with rich and often complicated life histories, conditions, experiences, and stories -- all of which hold valuable context around contributing or complicating factors that both shape health and affect rehabilitation/health-care outcomes.

In this chapter, we zoom out and investigate the effect that social determinants of health (SDOH) have on health over the course of one's lifetime and across generations. SDOH include interdependent social, economic, political, cultural, and environmental factors. For simplicity in this chapter, these factors are collectively referred to as SDOG or "social conditions" and are seen as a vital part of the "E" in the BME framework. We will investigate the relationships between SDOH, behavior, and biology to illuminate new approaches to health care.