Inheritance is a powerful concept employed in computer science, especially in artificial intelligence (AI), object-oriented programming (OOP), and object-oriented databases (OODB). In the field of AI, inheritance has been primarily used as a concise and effective means of representing and reasoning with common-sense knowledge (Thirunarayan, 1995). In programming languages and databases, inheritance has been used for the purpose of sharing data and methods, and for enabling modularity of software (re)use and maintenance (Lakshmanan & Thirunarayan, 1998). In this chapter, we present various design choices for incorporating inheritance into programming languages from an application programmer’s perspective. In contrast with the language of mathematics, which is mature and well-understood, the embodiment of object-oriented concepts and constructs in a concrete programming language is neither fixed nor universally accepted. We exhibit programs with similar syntax in different languages that have very different semantics, and different looking programs that are equivalent. We compare and contrast method inheritance, interaction of type system with method binding, constructs for method redefinition, and their implementation in widely used languages such as C++ (Stroustrup, 1997), Java (Arnold, Gosling, & Holmes, 2005), and C# (Hejlsberg, Wiltamuth, & Golde, 2006), to illustrate subtle issues of interest to programmers. Finally, we discuss multiple inheritance briefly.