Domestic serial holdings and cancellation data for science titles for the years 1992 through 1994 were collected from ten ARL libraries throughout the United States, based on their use of the F. W. Faxon Company as their primary domestic serial vendor and with their permission. The Library of Congress classification Q (science) was selected for further analysis. The Q and, more specifically, the QD (chemistry) data are analyzed to determine national trends in chemistry serial holdings and cancellations for the years 1992, 1993, and 1994. Findings show duplication among science subscriptions to be higher than for serial collections as a whole and that chemistry serial collections had the highest dollar value of serial cancellations during the three-year study period.