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Article
Nicotine Increases Osteoblast Activity in In Vitro Cell Culture in a Dose Dependent Manner
The Spine Journal
  • Scott D. Daffner
  • John France
  • Chad Smalley
  • Stacey Waugh
  • Timothy L. Norman, Cedarville University
  • Nina Clovis
  • Suzanne Smith
  • Vincent Kish
  • Nilay Mukherjee
Document Type
Conference Proceeding
Publication Date
10-1-2009
DOI
http://dx.doi.org/10.1016/j.spinee.2009.08.066
Abstract

BACKGROUND CONTEXT: Prior studies by our group have shown that nicotine delivered via a transdermal nicotine patch significantly enhanced posterior spinal fusion rates in rabbits. This runs contrary to previously published studies by other groups in which nicotine administration decreased fusion rates. Hence, there may be a dose-dependent effect of nicotine on posterior spinal fusion outcomes.

Citation Information
Scott D. Daffner, John France, Chad Smalley, Stacey Waugh, et al.. "Nicotine Increases Osteoblast Activity in In Vitro Cell Culture in a Dose Dependent Manner" The Spine Journal Vol. 9 Iss. 10 (2009) p. 28S
Available at: http://works.bepress.com/timothy_norman/111/