Presentation
Low Dose Nicotine Exposure Improves Posterior Spinal Fusion in an In Vivo Rabbit Model
24th North American Spine Society (NASS) Annual Meeting
Document Type
Conference Presentation
Event Date
11-10-2009
Location
San Fancisco, CA
Abstract
BACKGROUND CONTEXT: A previous pilot study by our group demonstrated that nicotine administration via transdermal nicotine patch showed consistent serum nicotine levels whereas administration via the more commonly utilized mini-osmotic pump resulted in large variations in serum levels of nicotine of rabbits. In other work, we have previously demonstrated that nicotine delivered via a transdermal patch enhanced posterior spinal fusion rates in rabbits. This is contrary to studies published by other groups where nicotine administration decreased fusion rates.
Disciplines
Citation Information
John France, Scott D. Daffner, Chad Smalley, Stacey Waugh, et al.. "Low Dose Nicotine Exposure Improves Posterior Spinal Fusion in an In Vivo Rabbit Model" 24th North American Spine Society (NASS) Annual Meeting (2009) Available at: http://works.bepress.com/timothy_norman/104/