Article
Sheathless Electrospray Ionization Interfaces for Capillary Electrophoresis-Mass Spectrometric Detection Advantages and Limitations
Journal of Chromatography A
Document Type
Article
Publication Date
10-22-2004
DOI
15543970
Abstract
A review of sheathless interfaces for capillary electrophoresis (CE)-mass spectrometry (MS) is presented. The review discusses the on-line CE-MS system requirements, advantages and weaknesses of current sheathless interface designs for CE-electrospray ionization MS, and comparison between sheath flow and sheathless interfaces. The advantages and limitations of three sheathless designs are discussed and commented upon, these include single-capillary, two-capillary and three-piece designs.
Disciplines
Keywords
- Electrophoresis,
- capillary,
- spectrometry,
- mass,
- electrospray ionization
Citation Information
Haleem J. Issaq, George M. Janini, King C. Chan and Timothy D. Veenstra. "Sheathless Electrospray Ionization Interfaces for Capillary Electrophoresis-Mass Spectrometric Detection Advantages and Limitations" Journal of Chromatography A Vol. 1053 Iss. 1-2 (2004) p. 37 - 42 ISSN: 0021-9673 Available at: http://works.bepress.com/timothy-veenstra/267/