Skip to main content
Article
CD30⁺ Reversible Lymphoid Dyscrasia (Pseudolymphoma) Following HIDA Scintigraphy and the [Ring1]-[Ring2]-[C=O] Generalized Structure Hypothesis
Journal of the American Academy of Dermatology
  • Ryan K. Rader
  • William V. Stoecker, Missouri University of Science and Technology
  • Kristen A. Hinton
  • Janine C. Malone
  • Thomas P. Schuman, Missouri University of Science and Technology
Abstract

To the Editor: Eighteen days after hepatobiliary iminodiacetic acid (HIDA) scintigraphy, an 81-year-old woman presented with pruritic, painful, discrete, tender papules in a generalized distribution (Fig 1). She noted onset of the eruption shortly after the HIDA scan. Biopsy specimen of 2 papules from the right thigh showed an infiltration of mitotically active lymphocytes (Fig 1, top inset) confined to the upper dermis. The lymphocytes were predominantly CD3+ T cells; occasional scattered CD20+ B cells were present. CD4 and CD8 were present in an approximately 2:1 ratio, and both cell types were noted within the epidermis. Small aggregates of large CD3+/CD30+ lymphocytes were present, comprising less than 25% of the lymphoid population (Fig 1, bottom inset). The histopathology and immunostaining supported a diagnosis of CD30+ plasma cell dyscrasia (pseudolymphoma).

Department(s)
Chemistry
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2013 Elsevier, All rights reserved.
Publication Date
1-1-2013
Publication Date
01 Jan 2013
Disciplines
Citation Information
Ryan K. Rader, William V. Stoecker, Kristen A. Hinton, Janine C. Malone, et al.. "CD30⁺ Reversible Lymphoid Dyscrasia (Pseudolymphoma) Following HIDA Scintigraphy and the [Ring1]-[Ring2]-[C=O] Generalized Structure Hypothesis" Journal of the American Academy of Dermatology (2013)
Available at: http://works.bepress.com/thomas-schuman/5/