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Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita
Nature Biotechnology
  • Pierre Abad, INRA, UMR
  • Jérôme Gouzy, INRA/CNRS
  • Jean-Marc Aury, Université d'Evry
  • Philippe Castagnone-Sereno, INRA, UMR
  • Etienne G J Danchin, INRA, UMR
  • Emeline Deleury, INRA, UMR
  • Laetitia Perfus-Barbeoch, INRA, UMR
  • Véronique Anthouard, Université d'Evry
  • Francois Artiguenave, Université d'Evry
  • Vivian C Blok, SCRI, Invergowrie
  • Marie-Cécile Caillaud, INRA, UMR
  • Pedro M Coutinho, Universités d'Aix-Marseille
  • Corinne Dasilva, Université d'Evry
  • Francesca De Luca, Consiglio Nazionale delle Ricerche
  • Florence Deau, INRA, UMR
  • Magali Esquibet, Univ. Rennes I
  • Timothé Flutre, Unité de Recherche en Génomique et Informatique (URGI)
  • Jared V Goldstone, Woods Hole Oceanographic Institution
  • Noureddine Hamamouch, North Carolina State University
  • Tarek Hewezi, Iowa State University
  • Olivier Jaillon, Université d'Evry
  • Claire Jubin, Université d'Evry
  • Paola Leonetti, Consiglio Nazionale delle Ricerche
  • Marc Magliano, INRA, UMR
  • Tom R. Maier, Iowa State University
  • Gabriel V Markov, Université de Lyon
  • Paul McVeigh, Queen's University Belfast
  • Graziano Pesole, University of Bari
  • Julie Poulain, Université d'Evry
  • Marc Robinson-Rechavi, University of Lausanne
  • Erika Sallet, GIS Toulouse Genopole
  • Béatrice Ségurens, Université d'Evry
  • Delphine Steinbach, Unité de Recherche en Génomique et Informatique (URGI)
  • Tom Tytgat, Wageningen University
  • Edgardo Ugarte, Université d'Evry
  • Cyril van Ghelder, INRA, UMR
  • Pasqua Veronico, Consiglio Nazionale delle Ricerche
  • Thomas J Baum, Iowa State University
  • Mark Blaxter, University of Edinburgh
  • Teresa Bleve-Zacheo, Consiglio Nazionale delle Ricerche
  • Eric L Davis, North Carolina State University
  • Jonathan J Ewbank, INSERM/CNRS/Université de la Méditerranée
  • Bruno Favery, INRA, UMR
  • Eric Grenier, Univ. Rennes I
  • Bernard Henrissat, Universités d'Aix-Marseille
  • John T Jones, SCRI, Invergowrie
  • Vincent Laudet, Université de Lyon
  • Aaron G Maule, Queen's University Belfast
  • Hadi Quesneville, Unité de Recherche en Génomique et Informatique (URGI)
  • Marie-Noëlle Rosso, INRA, UMR
  • Thomas Schiex, Unité de Biométrie et d'Intelligence Artificielle
  • Geert Smant, Wageningen University
  • Jean Weissenbach, Université d'Evry
  • Patrick Wincker, Université d'Evry
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Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall–degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

This article is published as Abad, Pierre, Jérôme Gouzy, Jean-Marc Aury, Philippe Castagnone-Sereno, Etienne GJ Danchin, Emeline Deleury, Laetitia Perfus-Barbeoch et al. "Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita." Nature biotechnology 26, no. 8 (2008): 909-915, doi: 10.1038/nbt.1482. Posted with permission.

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Pierre Abad, Jérôme Gouzy, Jean-Marc Aury, Philippe Castagnone-Sereno, et al.. "Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita" Nature Biotechnology Vol. 26 Iss. 8 (2008) p. 303 - 315
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