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A Root-Knot Nematode Secretory Peptide Functions as a Ligand for a Plant Transcription Factor
Molecular Plant-Microbe Interactions
  • Guozhong Huang, University of Georgia
  • Ruihua Dong, University of Georgia
  • Rex Allen, University of Georgia
  • Eric L. Davis, North Carolina State University
  • Thomas J. Baum, Iowa State University
  • Richard S. Hussey, University of Georgia
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Publication Version
Published Version
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Parasitism genes expressed in the esophageal gland cells of root-knot nematodes encode proteins that are secreted into host root cells to transform the recipient cells into enlarged multinucleate feeding cells called giant-cells. Expression of a root-knot nematode parasitism gene which encodes a novel 13-amino-acid secretory peptide in plant tissues stimulated root growth. Two SCARECROW-like transcription factors of the GRAS protein family were identified as the putative targets for this bioactive nematode peptide in yeast two-hybrid analyses and confirmed by in vitro and in vivo coimmunoprecipitations. This discovery is the first demonstration of a direct interaction of a nematode-secreted parasitism peptide with a plant-regulatory protein, which may represent an early signaling event in the root-knot nematode-host interaction.

This article is published as Huang, Guozhong, Ruihua Dong, Rex Allen, Eric L. Davis, Thomas J. Baum, and Richard S. Hussey. "A root-knot nematode secretory peptide functions as a ligand for a plant transcription factor." Molecular Plant-Microbe Interactions19, no. 5 (2006): 463-470, doi: 10.1094/MPMI-19-0463. Posted with permission.

Copyright Owner
The American Phytopathological Society
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Citation Information
Guozhong Huang, Ruihua Dong, Rex Allen, Eric L. Davis, et al.. "A Root-Knot Nematode Secretory Peptide Functions as a Ligand for a Plant Transcription Factor" Molecular Plant-Microbe Interactions Vol. 19 Iss. 5 (2006) p. 463 - 470
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