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Nematode effector proteins: an emerging paradigm of parasitism
New Phytologist
  • Melissa G. Mitchum, University of Missouri
  • Richard S. Hussey, University of Georgia
  • Thomas J. Baum, Iowa State University
  • Xiaohong Wang, United States Department of Agriculture
  • Axel A. Elling, Washington State University
  • Martin Wubben, United States Department of Agriculture
  • Eric L. Davis, North Carolina State University
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Phytonematodes use a stylet and secreted effectors to modify host cells and ingest nutrients to support their growth and development. The molecular function of nematode effectors is currently the subject of intense investigation. In this review, we summarize our current understanding of nematode effectors, with a particular focus on proteinaceous stylet-secreted effectors of sedentary endoparasitic phytonematodes, for which a wealth of information has surfaced in the past 10 yr. We provide an update on the effector repertoires of several of the most economically important genera of phytonematodes and discuss current approaches to dissecting their function. Lastly, we highlight the latest breakthroughs in effector discovery that promise to shed new light on effector diversity and function across the phylum Nematoda.

This article is published as Mitchum, Melissa G., Richard S. Hussey, Thomas J. Baum, Xiaohong Wang, Axel A. Elling, Martin Wubben, and Eric L. Davis. "Nematode effector proteins: an emerging paradigm of parasitism." New Phytologist 199, no. 4 (2013): 879-894, doi: 10.1111/nph.12323.

Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.
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Melissa G. Mitchum, Richard S. Hussey, Thomas J. Baum, Xiaohong Wang, et al.. "Nematode effector proteins: an emerging paradigm of parasitism" New Phytologist Vol. 199 Iss. 4 (2013) p. 879 - 894
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