Skip to main content
Other
Modeling Placebo Response Via Infinite Mixtures
2010 JSM Proceedings: Papers Presented at the Joint Statistical Meeting
  • Thaddeus Tarpey
Document Type
Conference Proceeding
Publication Date
8-5-2010
Catalog Record
Catalog Record
Abstract
Nonspecific treatment response, also known as placebo response, is ubiquitous in the treatment of mental illness, particularly in treating depression. The study of placebo effect is complicated because the factors that constitute nonspecific treatment effects are latent and not directly observed. A flexible infinite mixture model is introduced to model these nonspecific treatment effects. The infinite mixture model stipulates that the nonspecific treatment effects are continuous and this is contrasted with a finite mixture model that is based on the assumption that the nonspecific treatment effects are discrete. Data from a depression clinical trial is used to illustrate the model and to study the evolution of the placebo effect over the course of treatment.
Comments

This paper was presented at the Joint Statistical Meeting in Vancouver, BC, August 5, 2010.

Citation Information
Thaddeus Tarpey. "Modeling Placebo Response Via Infinite Mixtures" 2010 JSM Proceedings: Papers Presented at the Joint Statistical Meeting (2010) ISSN: 9780979174797
Available at: http://works.bepress.com/thaddeus_tarpey/36/