Prior research has established that there is a cumulative effect of risk factors on both youth violence and gang membership and that risk factors in multiple domains increase the probability of youth violence and gang involvement. In this article we expand upon this risk factor approach to the study of youth violence by addressing two questions concerning youth violence: (1) What are the effects of cumulative risk, including risk in multiple domains, on youth violence and gang membership and to what extent are the patterns similar or different for youth violence and gang membership? (2) To what extent do risk factors exert independent effects when other factors are controlled in multivariate analyses, and are the risk factors for youth violence similar to or different from those for gang membership? We utilise survey data from a sample of 5,395 8th grade students in 11 cities across the United States to examine these issues.