Interethnic interactions are often characterized by anxiety, discomfort, and increased awareness of both the self and the interaction partner, which may compound the likelihood of these interactions resulting in negative outcomes. This necessitates further examination of the psychological experience of interethnic interactions. One such piece of the psychological experience is awareness of one’s own ethnicity during interethnic interactions. In the current study, 449 adults of all ethnic identifications completed measures assessing ethnic awareness during interethnic interactions, ethnicity-related experiences, and mental health. African-Americans reported the greatest amount of ethnic awareness, and also endorsed significantly more ethnic awareness during social interactions than Whites. Ethnic awareness was also found to correlate well with measures of ethnic identity, racial microaggressions, perceived stress, depression, and hostility. Future research may wish to construct and validate a psychometrically sound measure of ethnic awareness in social interactions, incorporating the construct into examinations of race-related stress and other aspects of multicultural psychology.