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Taher Reza Kermanshahi, M.D.
Article
Hematochezia Associated with Sevalamer-Induced Mucosal Injury.
ACG Case Reports Journal (2014)
  • Preethi Chintamaneni, University of Pittsburgh
  • Rohit Das, University of Pittsburgh
  • Shih-Fan Kuan, University of Pittsburgh
  • Taher R. Kermanshahi, Beaumont Health
  • Jana G. Hashash, University of Pittsburgh
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Abstract
We present a case of a 61-year-old woman with end-stage renal disease (ESRD) who developed painless hematochezia following initiation of anticoagulation. Work-up revealed a large ulceration in the sigmoid colon, and histologic images revealed sevelamer crystals embedded in the colonic mucosa, consistent with sevelamer crystal-mediated injury. This is a novel cause of gastrointestinal hemorrhage that has not previously been described in the literature. Physicians should be aware of the potential for sevelamer-induced injury.
Disciplines
Publication Date
April 4, 2014
DOI
10.14309/CRJ.2014.32
Citation Information
Chintamaneni P, Das R, Kuan SF, Kermanshahi TR, Hashash JG. Hematochezia Associated with Sevalamer-Induced Mucosal Injury. ACG Case Rep J. 2014 Apr 4;1(3):145-7. doi: 10.14309/crj.2014.32. PMID: 26157856; PMCID: PMC4435309.