Scholars have expanded the academic literature to understand the way culture may influence politics but much less work has considered the influence of region on cities and individuals. The article uses existing data to examine whether liberalism is influenced by the region where individuals and cities are located. The study uses the boolean method and Hierarchical Linear Modeling to control for both individual and city level effects in 8 Canadian cities and 46 U.S. cities. The findings support the supposition that place still matters even in an era when globalization threatens to standardize much of what makes up our communities.