Unpublished Paper
Exposure to Heat Stress and anImmune Stimulus AffectsGene Expression in Chicken Immune Tissues
Animal Industry Report
Extension Number
ASL R3174
Publication Date
2017
Disciplines
Topic
Poultry
Summary and Implications
Gene expression changes after exposure to acute heatstress and/or to bacteriallipopolysaccharide (LPS) were investigated by measuring globalgene expression in two immune organs,bursa and thymus,from two chicken lines, Fayoumi and broiler. Over 1,600genes had significant expression changes in response to treatment; greaternumberswere identified in bursa for Fayoumi and in thymus forbroilers. Heat stress suppressed gene expression responses to LPS in both tissues.Both Heat and LPS impacted expression of immune cell traffickinggenes; these pathwaysneed to be investigated for potential to improve immune responses in heat-stressed chickens.
Copyright Holder
Iowa State University
Copyright Date
2017
DOI
https://doi.org/10.31274/ans_air-180814-289
Language
en
Citation Information
Melissa S. Monson, Angelica G. Van Goor, Christopher M. Ashwell, Michael E. Persia, et al.. "Exposure to Heat Stress and anImmune Stimulus AffectsGene Expression in Chicken Immune Tissues" (2017) Available at: http://works.bepress.com/susan_lamont/85/