Whole-genome or genomic selection is based on associations of large number of markers across the genome with phenotype but will require use of small SNP panels to be cost effective in chickens. The potential loss of accuracy of genotyping selection candidates with an evenly-spaced low-density marker panel and imputation of high-density SNP genotypes was evaluated in a commercial broiler chicken line. Several methods were used to estimate marker effects. The loss in accuracy was less than 5% for different methods and traits. Thus, genomic selection using evenly-spaced low-density marker panels is a cost-effective choice for implementation of genomic selection.