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Unpublished Paper
Genetic Diversity of the Antiviral Mx Gene in 14 Chicken Lines
Animal Industry Report
  • Patricia Davison, National Science Foundation Research Experience for Undergraduates
  • Michael G. Kaiser, Iowa State University
  • Susan J. Lamont, Iowa State University
  • Charles F. Curtiss, Iowa State University
Extension Number
ASL R2330
Publication Date
2008
Topic
Poultry
Summary and Implications

Genetic resistance to avian influenza has previously been associated with a Ser631Asn mutation of the chicken Mx gene. A portion of the Mx gene from 14 genetically diverse chickens lines were PCR amplified and sequenced. The Ser631Asn mutation showed genetic variation among the Iowa State University chicken lines, with some lines having the resistant allele while other lines had the susceptible allele. The diversity in the Mx gene warrants future studies into contrasting host resistance after viral infection in these Iowa State University lines.

Copyright Holder
Iowa State University
Language
en
Citation Information
Patricia Davison, Michael G. Kaiser, Susan J. Lamont and Charles F. Curtiss. "Genetic Diversity of the Antiviral Mx Gene in 14 Chicken Lines" (2008)
Available at: http://works.bepress.com/susan_lamont/11/