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Synthesis and characterization of Zinc/Chitosan-Folic acid complex
Heliyon (2018)
  • Subhani Bandara, Prairie View A&M University
  • Codi-anne Carnegie
  • Chevaun Johnson
  • Feyisayo Akindoju
  • Ebonee Williams
  • Julia M. Swaby
  • Aderemi Oki
  • Laura Carson, Prairie View A&M University
Abstract
Therapeutic drug delivery systems using polymeric materials is an emergingfield ofresearch. However, the use of certain polymers has gained much-needed attentionby the researchers due to their low toxic nature. In recent years, chitosan has gainedpopularity as a potential biodegradable polymer that can be used as a component indrug delivery systems. In this study, we synthesized a chitosan derivative that iscomposed of both folic acid and zinc and may serve as a viable component of adrug delivery system. The results of Fourier Transform Infrared Spectroscopy(FTIR), solid-state13C Nuclear Magnetic Resonance Spectroscopy (NMR) andUV-visible Spectroscopy demonstrated a substantial difference between chitosanand ZnS/Chitosan-Folic acid derivative. The results were also confirmed usingThermogravimetric Analysis (TGA) and Scanning Electron Microscopy/EnergyDispersive X-ray Spectroscopy (SEM-EDS) techniques. The average particle sizeof the ZnS/Chitosan-Folic acid system was measured to be 463.675.76 nm,showing that the product is within the nano-size range.
Disciplines
Publication Date
Summer August 13, 2018
Citation Information
Subhani Bandara, Codi-anne Carnegie, Chevaun Johnson, Feyisayo Akindoju, et al.. "Synthesis and characterization of Zinc/Chitosan-Folic acid complex" Heliyon (2018)
Available at: http://works.bepress.com/subhani-bandara/3/