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Nucleic acid delivery with α-tocopherol-polyethyleneimine-polyethylene glycol nanocarrier system
International Journal of Nanomedicine (2020)
  • A K M Nawshad Hossian, University of Louisiana at Monroe
  • Seetharama D Jois, University of Louisiana at Monroe
  • Subash C Jonnalagadda, Rowan University
  • George Mattheolabakis, University of Louisiana at Monroe
Abstract
Nucleic acid-based therapies are a promising therapeutic tool. The major obstacle in their clinical translation is their efficient delivery to the desired tissue. We developed a novel nanosized delivery system composed of conjugates of α-tocopherol, polyethyleneimine, and polyethylene glycol (TPP) to deliver nucleic acids.
Disciplines
Publication Date
September 11, 2020
DOI
10.2147/IJN.S259724
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Citation Information
A K M Nawshad Hossian, Seetharama D Jois, Subash C Jonnalagadda and George Mattheolabakis. "Nucleic acid delivery with α-tocopherol-polyethyleneimine-polyethylene glycol nanocarrier system" International Journal of Nanomedicine Vol. 15 (2020) p. 6689 - 6703
Available at: http://works.bepress.com/subash-jonnalagadda/11/
Creative Commons license
Creative Commons License
This work is licensed under a Creative Commons CC_BY-NC International License.