This study examined how past information-seeking experience influences individuals’ information-seeking decision process following an event that increases uncertainty in close relationships. To examine this issue, a two-wave, cross-lagged, panel-design study was conducted, and outcome expectancy, communication efficacy, and information-seeking were measured at each time. Analyses revealed that communication efficacy mediates the link between outcome expectancies and information-seeking under the conditions of uncertainty. The results also suggest that communication efficacy and information-seeking impact each other cyclically. The findings of this research suggest that scholars should focus on people's information-seeking experience and communication efficacy when examining information-seeking following events that increase uncertainty in close relationships.