The livestock and poultry production industry lacks a current, science-based guide for evaluation of air quality mitigation technologies. Therefore, we performed a science-based review of mitigation technologies using practical, stakeholders-oriented evaluation criteria to identify knowledge gaps/needs and focuses for future research efforts on technologies and areas with the greatest impact potential. Our objectives were to (1) present a recently completed Literature Database, and (2) identify and rank research needs and knowledge gaps based on the Literature Database. The Air Management Practices Tool (AMPAT) is web-based (available at www.agronext.iastate.edu/ampat) and provides an objective overview of mitigation practices best suited to address odor, gaseous, and particulate matter (PM) emissions at livestock operations. This tool helps livestock and poultry producers compare and explore different mitigation technologies. Simultaneously, a literature review of 267 papers was performed to evaluate mitigation technologies performance for emissions of odor, VOCs, NH3, H2S, PM, and GHGs and inform future research needs. Swine production systems were the most researched with 52% of the data entries. Housing and manure storage were the most researched sources of emissions with 41 and 43% of the data entries respectively. Biofilters were the most popular and farm tested technology for reducing emissions from animal housing. Aeration, anaerobic digestion, composting, diet manipulation and covers were the most researched technologies for reducing emission during manure storage and handling, with aeration being the most effective means of odor reduction farm scale tested. Injection or incorporation was the most farm tested and effective technology researched for land application.