Article
Selectable viruses and altered susceptibility mutants in Arabidopsis thaliana
Proceedings of the National Academy of Sciences of the United States of America
(1999)
Abstract
The genetic basis for susceptibility or nonsusceptibility
of plants to viruses is understood poorly. Two
selectable tobacco etch virus (TEV) strains were developed for
identification of Arabidopsis thaliana mutants with either
gain-of-susceptibility or loss-of-susceptibility phenotypes.
These strains conferred a conditional-survival phenotype to
Arabidopsis based on systemic expression of herbicide resistance
or proherbicide sensitivity genes, thereby facilitating
mass selections and screens for Arabidopsis mutants that
enhance or suppress TEV replication, cell-to-cell movement,
or long-distance movement. A multicomponent mechanism
that restricts systemic invasion of TEV was identified through
isolation of gain-of-susceptibility mutants with alterations at
two loci.
Disciplines
Publication Date
1999
DOI
10.1073/pnas.96.2.772
Publisher Statement
This article is from Proceedings of the National Academy of Sciences of the United States of America 96 (1999): 772, doi:10.1073/pnas.96.2.772. Posted with permission.
Citation Information
Steven A. Whitham, Miki L. Yamamoto and James C. Carrington. "Selectable viruses and altered susceptibility mutants in Arabidopsis thaliana" Proceedings of the National Academy of Sciences of the United States of America Vol. 96 Iss. 2 (1999) p. 772 - 777 Available at: http://works.bepress.com/steven-whitham/12/