The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol.
Pipingas, A, Sinclair, A, Croft, KD, Januszewski, AS, Jenkins, AJ, Mori, TA, Cockerell, R, Grima, NA, Stough, C, Scholey, A, Myers, SP, Sali, A & Pase, MP 2015, 'Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial', Journal of Functional Foods, vol. 19, pt. B, pp. 949-957.
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