Skip to main content
Article
Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial
Journal of Functional Foods
  • Andrew Pipingas, Swinburne University of Technology
  • Andrew Sinclair, Deakin University
  • Kevin D Croft, University of Western Australia
  • Andrzej S Januszewski, University of Melbourne
  • Alicia J Jenkins, University of Melbourne
  • Trevor A Mori, University of Western Australia
  • Robyn Cockerell, Swinburne University of Technology
  • Natalie A Grima, Monash University
  • Con Stough, Swinburne University of Technology
  • Andrew Scholey, Swinburne University of Technology
  • Stephen P Myers, Southern Cross University
  • Avni Sali, National Institute of Integrative Medicine, Melbourne
  • Matthew P Pase, Swinburne University of Technology
Document Type
Article
Publication Date
1-1-2015
Peer Reviewed
Peer-Reviewed
Abstract
The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol.
Citation Information

Pipingas, A, Sinclair, A, Croft, KD, Januszewski, AS, Jenkins, AJ, Mori, TA, Cockerell, R, Grima, NA, Stough, C, Scholey, A, Myers, SP, Sali, A & Pase, MP 2015, 'Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial', Journal of Functional Foods, vol. 19, pt. B, pp. 949-957.

Published version available from:

http://dx.doi.org/10.1016/j.jff.2014.10.028