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Article
Natural Hyperthermia and Expression of the Heat Shock Protein Hsp70 Affect Developmental Abnormalities in Drosophila Melanogaster
Oecologia
  • Stephen P. Roberts, Missouri University of Science and Technology
  • Martin E. Feder
Abstract

We Demonstrate that Natural Heat Stress on Wild Larval Drosophila Melanogaster Results in Severe Developmental Defects in >10% of Eclosing Adults, and that Increased Copy Number of the Gene Encoding the Major Inducible Heat Shock Protein of D. Melanogaster, Hsp70, is Sufficient to Reduce the Incidence of Such Abnormalities. Specifically, Non-Adult D. Melanogaster Inhabiting Necrotic Fruit Experienced Severe, Often Lethal Heat Stress in Natural Settings. Adult Flies Eclosing from Wild Larvae that Had Survived Natural Heat Stress Exhibited Severe Developmental Anomalies of Wing and Abdominal Morphology, Which Should Dramatically Affect Fitness. the Frequency of Developmental Abnormalities Varied Along Two Independent Natural Thermal Gradients, exceeding 10% in Adults Eclosing from Larvae Developing in Warm, Sunlit Fruit. When Exposed to Natural Heat Stress, D. Melanogaster Larvae with the Wild-Type Number of Hsp70 Genes (N=10) Developed Abnormal Wings Significantly More Frequently Than a Transgenic Sister Strain with 22 Copies of the Hsp70 Gene.

Department(s)
Biological Sciences
Comments

National Science Foundation, Grant IBN 97-23298

Keywords and Phrases
  • Development,
  • Drosophila melanogaster,
  • Heat shock proteins,
  • Hsp70,
  • Natural hyperthermia
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2023 Springer, All rights reserved.
Publication Date
11-1-1999
Publication Date
01 Nov 1999
Disciplines
Citation Information
Stephen P. Roberts and Martin E. Feder. "Natural Hyperthermia and Expression of the Heat Shock Protein Hsp70 Affect Developmental Abnormalities in Drosophila Melanogaster" Oecologia Vol. 121 Iss. 3 (1999) p. 323 - 329 ISSN: 0029-8549
Available at: http://works.bepress.com/stephen-roberts/38/