|2013 - Present||Director of Research, Nova Southeastern University ‐ Halmos College of Natural Sciences and Oceanography, Department of Biological Sciences|
Honors and Awards
- 1966-1971: NIH Genetics Traineeship
- 1971-1973: NIH Postdoctoral Fellowship
- 1972-1978: Co-Chairman and Founder, Mid-Atlantic Drosophila Society
- 1975-1976: Elected Council Representative, NCI Assembly of Scientists
- 1979-Present: Elected New York Academy of Science
- 1979-Present: Member, International Committee on Comparative Gene Mapping
- 1982-Present: Appointed Research Fellow of Smithsonian Institution, Washington DC
- 1983-Present: Elected Board of Trustees, American Type Culture Association, Rockville, MD
- 1984-Present: Appointed, Executive Board, American Type Culture Collection, Rockville, MD
- 1984-Present: Elected Board of Directors, American Genetics Association (AGA)
- 1985: National Geographic Society Research Award (for study of genetics and reproduction of East African cheetah)
- 1985-Present: Appointed, Chairman, Long Range Planning Committee, AGA
- 1985-Present: Founder and Co-Director, NOAHS (New Opportunities in Animal Health Sciences) Center for Wildlife Sciences, Smithsonian Institution
- 1985-Present: Member, Cat Specialist Group, International Union for Conservation of Nature, I.U.C.N., Geneva
- 1986: Recipient World Wildlife Fund Research Award (for study of genetic structure of relict populations of giant pandas)
- 1986-Present: Member, Captive Breeding Specialist Group, Species Survival Commission, I.U.C.N., Geneva
- 1986-Present: Advisor, Special Survival Plan - Cheetah, American Zoological Association
- 1987-Present: Secretary-Treasurer, Board of Trustees, American Type Culture Collection
- 1987-Present: Chairman, International Committee on Comparative Gene Mapping
- 1987-Present: Elected Member Cosmos Club, Washington, DC
- 1988: Explorer's Club Annual Dinner Prinipal Lecture Award in Commemoration of the 100th Anniversary of the National Geographic Society
- 1988-Present: Elected Fellow Explorer's Club, New York, NY
- 1994-Present: Elected Fellow of the American Academy of Arts and Sciences
- 1994: Distinguished Alumnus in Natural Sciences, St. Francis College, Loretto, PA
- 1997: Visiting Fellow, Merton College, Oxford University, Oxford
- 1998-Present: Elected Fellow, American Association for the Advancement of Science
- 1998: Oscar W. Schlam Lectureship Award School of Veterinary Medicine, University of California, Davis
- 1998-2004: Andrew Dixon White Professor-at-Large, Cornell University
- 2006: Chairman Board of Trustees Cheetah Conservation Fund
- 2006: Annual Citation Award for Outstanding Research in AIDS Cancer and Public Health
- University of St. Petersburg, St. Petersburg, Russia
- 2006: Institution of the Stephen J. O'Brien Award for Outstanding Paper Published by American Genetic Association
- 2009: Honorary Doctarate Degree in Veterinary Medicine conferred by the College of Veterinary Medicine, University of Zurich, Switzerland
- 2012: Senior Fellow, American Humane Association, USA
- 2018: Elected to National Academy of Sciences
|1971||Ph.D. Genetics, Cornell University|
|1966||B.S. Biology, St. Francis College|
Analytical “Bake-Off” of Whole Genome Sequencing Quality for the Genome Russia Project Using a Small Cohort for Autoimmune Hepatitis PLoS One (2018)
A comparative analysis of whole genome sequencing (WGS) and genotype calling was initiated for ten human genome samples sequenced by St. Petersburg State University Peterhof Sequencing Center and by three commercial sequencing centers outside of ...
Robust Forensic Matching of Confiscated Horns to Individual poached African rhinoceros Current Biology (2018)
Black and white rhinoceros (Diceros bicornis and Ceratotherium simum) are iconic African species that are classified by the International Union for the Conservation of Nature (IUCN) as Critically Endangered and Near Threatened (http://www.iucnredlist.org/), respectively. At ...
Conservation Genetics of the Cheetah: Lessons Learned and New Opportunities Journal of Heredity (2017)
The dwindling wildlife species of our planet have become a cause célèbre for conservation groups, governments, and concerned citizens throughout the world. The application of powerful new genetic technologies to surviving populations of threatened mammals ...
Mitogenomic Sequences Support a North–South Subspecies Subdivision within Solenodon paradoxus Mitochondrial DNA Part A (2017)
Solenodons are insectivores found only in Hispaniola and Cuba, with a Mesozoic divergence date versus extant mainland mammals. Solenodons are the oldest lineage of living eutherian mammal for which a mitogenome sequence has not been ...
Perspectives Provided by Leopard and Other Cat Genomes: How Diet Determined the Evolutionary History of Carnivores, Omnivores, and Herbivores BMB Reports (2017)
Recent advances in genome sequencing technologies have enabled humans to generate and investigate the genomes of wild species. This includes the big cat family, such as tigers, lions, and leopards. Adding the first high quality ...
Signal Localization: A New Approach in Signal Discovery Biometrical Journal (2017)
A new approach for statistical association signal identification is developed in this paper. We consider a strategy for nonprecise signal identification by extending the well-known signal detection and signal identification methods applicable to the multiple ...
Whole-Genome Identification, Phylogeny, and Evolution of the Cytochrome P450 Family 2 (CYP2) Subfamilies in Birds Genome Biology and Evolution (2016)
The cytochrome P450 (CYP) superfamily defends organisms from endogenous and noxious environmental compounds, and thus is crucial for survival. However, beyond mammals the molecular evolution of CYP2 subfamilies is poorly understood. Here, we characterized the ...
De Novo Sequencing, Assembly and Analysis of Eight Different Transcriptomes from the Malayan Pangolin Scientific Reports (2016)
Pangolins are scale-covered mammals, containing eight endangered species. Maintaining pangolins in captivity is a significant challenge, in part because little is known about their genetics. Here we provide the first large-scale sequencing of the critically ...
Positive Selection Linked with Generation of Novel Mammalian Dentition Patterns Genome Biology and Evolution (2016)
A diverse group of genes are involved in the tooth development of mammals. Several studies, focused mainly on mice and rats, have provided a detailed depiction of the processes coordinating tooth formation and shape. Here ...
Chromosomer: A Reference-Based Genome Arrangement Tool for Producing Draft Chromosome Sequences GigaScience (2016)
Background: As the number of sequenced genomes rapidly increases, chromosome assembly is becoming an even more crucial step of any genome study. Since de novo chromosome assemblies are confounded by repeat-mediated artifacts, reference-assisted assemblies that ...
Contrasting Origin of B Chromosomes in Two Cervids (Siberian Roe Deer and Grey Brocket Deer) Unravelled by Chromosome-Specific DNA Sequencing BMC Genomics (2016)
Background B chromosomes are dispensable and variable karyotypic elements found in some species of animals, plants and fungi. They often originate from duplications and translocations of host genomic regions or result from hybridization. In most ...
Continued Decline in Genetic Diversity Among Wild Cheetahs (Acinonyx jubatus) Without Further Loss of Semen Quality Biological Conservation (2016)
As a well-studied felid with limited genetic diversity, the cheetah (Acinonyx jubatus) has shaped much of the scientific debate surrounding inbreeding depression. The species survived a population bottleneck ~ 12,000 years ago and was extirpated ...
A High-Resolution SNP Array-Based Linkage Map Anchors a New Domestic Cat Draft Genome Assembly and Provides Detailed Patterns of Recombination G3 (2016)
High-resolution genetic and physical maps are invaluable tools for building accurate genome assemblies, and interpreting results of genome-wide association studies (GWAS). Previous genetic and physical maps anchored good quality draft assemblies of the domestic cat ...
Bone-Associated Gene Evolution and the Origin of Flight in Birds BMC Genomics (2016)
Background Bones have been subjected to considerable selective pressure throughout vertebrate evolution, such as occurred during the adaptations associated with the development of powered flight. Powered flight evolved independently in two extant clades of vertebrates, ...
A Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus) PLoS ONE (2016)
The glaucomas are a group of diseases characterized by optic nerve damage that together represent a leading cause of blindness in the human population and in domestic animals. Here we report a mutation in LTBP2 ...
The Asian Arowana (Scleropages formosus) Genome Provides New Insights into the Evolution of an Early Lineage of Teleosts Scientific Reports (2016)
The Asian arowana (Scleropages formosus), one of the world’s most expensive cultivated ornamental fishes, is an endangered species. It represents an ancient lineage of teleosts: the Osteoglossomorpha. Here, we provide a high-quality chromosome-level reference genome ...
Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding PLoS Genetics (2016)
We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer), a tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical and genetic mapping along with shared synteny from closely ...
Genetic Evidence for Contrasting Wetland and Savannah Habitat Specializations in Different Populations of Lions (Panthera leo) Journal of Heredity (2016)
South-central Africa is characterized by an archipelago of wetlands, which has evolved in time and space since at least the Miocene, providing refugia for animal species during Pleistocene arid episodes. Their importance for biodiversity in ...
The Population Origins and Expansion of Feral Cats in Australia Journal of Heredity (2016)
The historical literature suggests that in Australia, the domestic cat (Felis catus) had a European origin [~200 years before present (ybp)], but it is unclear if cats arrived from across the Asian land bridge contemporaneously ...
Genomic Legacy of the African Cheetah, Acinonyx jubatus Genome Biology (2015)
Background Patterns of genetic and genomic variance are informative in inferring population history for human, model species and endangered populations. Results Here the genome sequence of wild-born African cheetahs reveals extreme genomic depletion in SNV ...
The Genome Russia Project: Closing the Largest Remaining Omission on the World Genome Map GigaScience (2015)
We are witnessing the great era of genome exploration of the world, as genetic variation in people is being detailed across multiple varied world populations in an effort unprecedented since the first human genome sequence ...
Effect of Carcinoembryonic Antigen Production by Colorectal Cancer Cells on Tumor Microenvironment and Cancer Progression European Journal of Cancer Supplements (2015)
Tumor markers play an important role in the identification of human malignancies. It has been shown that the carcinoembryonic antigen (CEA, CEACAM5) is a promoter of metastasis in epithelial cancers that is widely used as ...