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Selected Works of Stephen O'Brien
Article
Whole Genome Sequence Coverage Estimation Re-examined
Biology Faculty Proceedings, Presentations, Speeches, Lectures
  • Alexey Antonik, St. Petersburg State University
  • Stephen J. O'Brien, St. Petersburg State University - Russia
  • Sergey Malov, St. Petersburg State University - Russia; St. Petersburg Electrotechnical University - Russia
Link
Event Name/Location
Applied Methods of Statistical Analysis: Applications in Survival Analysis, Reliability and Quality Control - Proceedings of the International Workshop / Novosibirsk, Russia
Presentation Date
9-1-2013
Document Type
Article
Keywords
  • Coverage Problem,
  • Spacings,
  • Uniform Spacings
Description

Novel methods for estimating the depth of whole genome sequencing required for adequate coverage are presented. Employing the notion of r-spacing existent results for the uniform coverage were extended for the large scope of non-uniform distributions.

Comments

pg. 46-50

Disciplines
Citation Information
Alexey Antonik, Stephen J. O'Brien and Sergey Malov. "Whole Genome Sequence Coverage Estimation Re-examined" (2013)
Available at: http://works.bepress.com/stephen-obrien/663/