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Epithelial Interleukin-8 Responses to Oral Bacterial Biofilms
Clinical and Vaccine Immunology (2011)
  • R. Peyyala, University of Kentucky
  • Sreenatha S. Kirakodu, University of Kentucky
  • K. F. Novak, University of Kentucky
  • J. L. Ebersole, University of Kentucky
An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses.
  • Bacteria,
  • Biofilms,
  • Epithelial Cells,
  • Host-Pathogen Interactions,
  • Interleukin-8,
  • Mouth Mucosa
Publication Date
October, 2011
Publisher Statement

Published in Clinical and Vaccine Immunology, v. 18, no. 10, p. 1770–1772.

Citation Information
R. Peyyala, Sreenatha S. Kirakodu, K. F. Novak and J. L. Ebersole. "Epithelial Interleukin-8 Responses to Oral Bacterial Biofilms" Clinical and Vaccine Immunology Vol. 18 Iss. 10 (2011)
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