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Contribution to Book
Pathophysiology of Clinical Disorders of Urine Concentration and Dilution
Pathophysiology of the Kidney
  • Manuel Martínez-Maldonado, University of Puerto Rico - School of Medicine
  • Susan C. Opava-Stitzer, University of Puerto Rico - School of Medicine
Publication Date
1-1-1977
Abstract

A defect in the ability to concentrate or dilute the urine can be easily recognized by the maximum or minimum urine concentration the patient is able to achieve. Maximum concentrating ability (Umax) is determined by the urine osmolality reached after a fixed period of dehydration and maximal diluting ability (Umin) by the minimum osmolality of the urine after the oral ingestion of a fixed water-load. These indices, however, do not allow an understanding of the pathophysiological alterations leading to the presence of the defect.

Disciplines
Citation Information
Manuel Martínez-Maldonado and Susan C. Opava-Stitzer. "Pathophysiology of Clinical Disorders of Urine Concentration and Dilution" Pathophysiology of the Kidney (1977) p. 992 - 1028
Available at: http://works.bepress.com/sopava/4/