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Article
New and emerging therapies for Melanoma
U.S. Pharmacist
  • Sonia Amin Thomas, Philadelphia College of Osteopathic Medicine
  • A. G. Douglas
  • A. Rose
  • E. Dingsangha
  • Valerie Tapia
Document Type
Article
Publication Date
1-1-2015
Abstract

Melanoma is a leading cause of skin cancer mortality in the United States. Treatment for melanoma had been limited to very few agents, including chemotherapy, with older treatment options such as interferon and interleukin-2 causing toxic adverse effects. Since the approval of the monoclonal antibody ipilimumab in 2011, there have been several new drugs approved for metastatic melanoma. Recently, there have been approvals of kinase inhibitors and programmed death receptor-1 (PD-1) inhibitors for unresectable or metastatic melanoma, including vemurafenib, nivolumab, and pembrolizumab. These agents have been considered breakthrough therapies in the treatment of melanoma.

Comments

This article was published in U.S. Pharmacist, Volume 40, Issue 11, Pages 3-6.

The published version is available at http://www.uspharmacist.com/supplements/s/394/.

Copyright © 2015 Jobson Medical Publishing.

Citation Information
Sonia Amin Thomas, A. G. Douglas, A. Rose, E. Dingsangha, et al.. "New and emerging therapies for Melanoma" U.S. Pharmacist Vol. 40 Iss. 11 (2015) p. 3 - 6
Available at: http://works.bepress.com/sonia_patel/7/