Article
Use of fecal volatile organic compound analysis to discriminate between non-vaccinated and BCG—Vaccinated cattle prior to and after Mycobacterium bovis challenge
PLoS ONE
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
7-7-2017
DOI
10.1371/journal.pone.0179914
Abstract
Bovine tuberculosis is a zoonotic disease of global public health concern. Development of diagnostic tools to improve test accuracy and efficiency in domestic livestock and enable surveillance of wildlife reservoirs would improve disease management and eradication efforts. Use of volatile organic compound analysis in breath and fecal samples is being developed and optimized as a means to detect disease in humans and animals. In this study we demonstrate that VOCs present in fecal samples can be used to discriminate between non-vaccinated and BCG-vaccinated cattle prior to and after Mycobacterium bovis challenge.
Access
Open
Rights
This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
Language
en
File Format
application/pdf
Citation Information
Christine K. Ellis, Somchai Rice, Devin Maurer, Randal Stahl, et al.. "Use of fecal volatile organic compound analysis to discriminate between non-vaccinated and BCG—Vaccinated cattle prior to and after Mycobacterium bovis challenge" PLoS ONE Vol. 12 Iss. 7 (2017) p. e0179914 Available at: http://works.bepress.com/somchai_rice/5/
This article is from PLoS ONE 12(7): e0179914. https://doi.org/10.1371/journal.pone.0179914.