Qualitative interviewing is a flexible and powerful tool to capture the voices and the ways people make meaning of their experience Learning to conduct semi-structure interviews requires the following six stages: (a) selecting the type of interview; (b) establishing ethical guidelines, (c) crafting the interview protocol; (d) conducting and recording the interview; (e) crafting the interview protocol; and (f) reporting the findings. A researcher’s personal journey in crafting an interview protocol to interview HIV researchers is summarized. She highlights that training and experience are crucial and identifies some readings that can help in the process.