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Barriers to Participation in a Randomized Controlled Trial of
Asian Pacific J Cancer Prev (2012)
  • Siew Yim Loh, Assoc Prof, University of Malaya
range from patient-related, through institutional-related to staff-related factors. This paper highlights the low response rate and the recruitment barriers faced in our Qigong exercises trial. Materials and Method: The Qigong trial is a three-arm trial with a priori power size of 114 patients for 80% power. The University Malaya Medical Centre database showed a total of 1,933 patients from 2006-2010 and 751 patients met our inclusion criteria. These patients were approached via telephone interview. 131 out of 197 patients attended the trial and the final response rate was 48% (n=95/197). Results: Multiple barriers were identified, and were regrouped as patientrelated, clinician-related and/or institutional related. A major consistent barrier was logistic difficulty related to transportation and car parking at the Medical Centre. Conclusions: All clinical trials must pay considerable attention to the recruitment process and it should even be piloted to identify potential barriers and facilitators to reduce attrition rate in trials.
  • Cancer,
  • cancer survivors,
  • QiGong,
  • Physical Activity,
  • Lifestyle,
  • RCT,
  • barriers
Publication Date
Citation Information
Siew Yim Loh. "Barriers to Participation in a Randomized Controlled Trial of" Asian Pacific J Cancer Prev Vol. 13 Iss. 12 (2012)
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