The foliar, stem, and root diseases of soybeans are significant components of yield loss in soybean fields. Use of fungicides is one of the options in management of soybean diseases. According to USDA-NASS, fungicide use in soybean has increased from <1 percent in 2002 to 11 percent of soybean planted acres in 2012 in 20 soybean producing states (Arkansas, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maryland, Michigan, Minnesota, Mississippi, Missouri, Nebraska, North Carolina, North Dakota, Ohio, South Dakota, Tennessee, Virginia, and Wisconsin). The objectives of these trials were to test efficacy of various foliar fungicides sprayed at R3 growth stage on disease control and yield response during 2012 and 2013 growing seasons.