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Article
Investigating The Association Between Chronic Kidney Disease and Clinical Outcomes.
Appalachian Student Research Forum
  • Naveen Ramzan
  • Shimin Zheng, East Tennessee State Univeristy
  • Hemang Panchal, East Tennessee State University
  • Edward Leinaar
  • Christian Nwabueze
  • Timir K Paul
Authors' Affiliations
Naveen Ramzan, Department of Biostatistics and Epidemiology, College of Public Health, ETSU, Johnson City, TN 37614. Dr. Shimin Zheng, Department of Biostatistics and Epidemiology, College of Public Health, ETSU, Johnson City, TN 37614 Christian Nwabueze, Department of Biostatistics and Epidemiology, College of Public Health, ETSU, Johnson City, TN 37614 Hemang Panchal, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, TN, 37614 Timir K.Paul, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, TN, 37614 Edward Leinaar, Department of Health Services Management and Policy, CPH, ETSU, Johnson City, TN 37614
Location
White Top Mtn
Start Date
4-12-2019 9:00 AM
End Date
4-12-2019 2:30 PM
Publication date
4-12-2019
Poster Number
111
Faculty Sponsor’s Department
Biostatistics & Epidemiology
Name of Project's Faculty Sponsor
Dr. Shimin Zheng
Classification of First Author
Graduate Student-Master’s
Type
Poster: Non-Competitive
Abstract or Artist's Statement

Background

Chronic Kidney Disease (CKD) can be described as the loss of the kidney function over time. Symptoms usually develop slowly, and it may not appear in early stages. Lab tests can confirm a CKD diagnosis. The approximate number of incidents per year is more than 200,000 cases, and approximately 30 million people are living with CKD today in the United States. This long-standing disease ultimately leads to renal failure at the end. At this present time, there are no known cures for CKD, and the only treatment available is dialysis. Objectives

The purpose of this study is to determine the association between CKD and further with hemodialysis (HD) and medical condition such as cardiac complications, cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications, and death. Study design

The study employed secondary data in a cross-sectional design. Methods

A sample of 106,969 was drawn from the population. The outcome variables were a diagnosis of CKD and/or CKD with HD. The predictor variables were cardiac complications, cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications and death. Logistic regression was conducted to analyze the relationship between outcome variable and each independent variable. Variables with a p-value Results

Analysis shows that subjects with cardiac complications were 17% less likely to have CKD as compared to those who did not have cardiac complications (OR: 0.83, 95% CI: 0.78-0.88). CKD patients who had cardiac complications were 18% more likely to have HD than the subjects who did not have cardiac complications (OR: 1.18, 95% CI: 1.01-1.39). Patients with cardiogenic shock were 86% more likely to have CKD than the subjects who did not have cardiogenic shock (OR: 1.86, 95% CI: 1.82-1.91). CKD patients who had cardiogenic shock were also 18% more likely to have HD than the subjects who did not have cardiogenic shock (OR: 1.18, 95% CI: 1.11-1.25). We have similar results if a patient had other conditions. Conclusion

Chronic kidney disease with hemodialysis is significantly associated by the other medical conditions such as cardiac complications cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications and death in the United States. Further studies are needed to confirm the results and to understand the prognosis.

Creative Commons License
Creative Commons Attribution 4.0 International
Citation Information
Naveen Ramzan, Shimin Zheng, Hemang Panchal, Edward Leinaar, et al.. "Investigating The Association Between Chronic Kidney Disease and Clinical Outcomes." (2019)
Available at: http://works.bepress.com/shimin-zheng/105/