In the field of sports science, the number/ percentage of IFN - 酌(or IL -2) and IL -4 cells in periph鄄 eral blood or spleen, the levels of Th1, Th2 - associated cytokines produced by the cells, and the concentrations of the cytokines in circulation are measured by researchers to evaluate the Th1/ Th2 balance following exercise from the per鄄 spective of Th1and Th2 cell numbers and function. The analysis believes that (1) The change of Th1 and Th2 cells in response to exercise is the same as that of Tc1 and Tc2 cells respectively, while Th1/ Th2 balance can be used as the in鄄 dicator of T1/ T2 balance indirectly. (2) The concentration of cytokines may be the more meaningful indicators of Th1/ Th2 balance in response to exercise than that of cell numbers. (3) The concentration of cytokines in the circulation may be the more meaningful indicators of Th1/ Th2 balance in response to exercise than that of cytokines produced by lym鄄 phocytes. The review is to provide the basis for study protocols and reference for discussions in the future researches through the reflection on the evaluation of Th1/ Th2 balance in response to exercise.
Zhao, GG, Su, QS, Zhou, S, He, JW, Su, LQ & Zhang, W, 2014, 'Reflection on the evaluation method of immune balance in exercise ', Journal of Chengdu Sport University, vol. 40, no. 12, pp. 79-84.