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Article
Insulin-like growth factor-I on skeletal muscle growth and repair of research progress
Journal of Tianjin Institute of Physical Education
  • Longjun Cao, Tianjin University of Sport
  • Liping Huang, Tianjin University of Sport
  • Shi Zhou, Southern Cross University
Document Type
Article
Publication Date
1-1-2006
Abstract
The growth hormone (GH)/insulin- like growth factor- I (IGF- I) axis is one of the most important regulators of skeletal muscle growth. Insulin- like growth factor- I is expressed in many tissues, however it may have different functions. Skeletal muscle is not only a target of the IGF- I, but also a producer. The IGF- I expressed in skeletal muscle has been suggested playing a key role in muscle regeneration and repair after injury. It is also an important regulatory factor in maintaining muscle quantity. This review summarized the current literature in this field, and discussed the potential significance and application of GH/IGF- I intervention in exercise rehabilitation.
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Citation Information
Cao, LJ, Huang, LP & Zhou, S 2006, 'Insulin-like growth factor-I on skeletal muscle growth and repair of research progress ', Journal of Tianjin Institute of Physical Education, vol. 21, no. 3, pp. 242-245.