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Can familial factors account for the association of body mass index with poor mental health in men or women
UMass Worcester Prevention Research Center Publications and Presentations
  • Ellen Schur, University of Washington
  • Kathryn M. Godfrey, San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology
  • Elizabeth Dansie, University of Washington
  • Dedra Buchwald, University of Washington
  • Sherry L. Pagoto, University of Massachusetts Medical School
  • Niloofar Afari, University of California, San Diego
UMMS Affiliation
Department of Medicine, Division of Preventive and Behavioral Medicine
Date
9-1-2013
Document Type
Article
Medical Subject Headings
Adult; *Body Mass Index; Cholestasis; Cross-Sectional Studies; Depression; Female; Health Status; Humans; Male; Mental Disorders; Obesity; Pneumonia; Psychiatric Status Rating Scales; Stress, Psychological
Abstract
OBJECTIVE: This study examined if associations between body mass index (BMI) and mental and physical health were independent of genetic and familial factors. METHOD: Data from 2831 twins (66% female) were used in an epidemiological co-twin control design with measures of BMI and mental and physical health outcomes. Generalized estimating equation regressions assessed relationships between BMI and health outcomes controlling for interdependency among twins and demographics. Within-pair regression analyses examined the association of BMI with health outcomes controlling for genetic and familial influences. RESULTS: Adjusted analyses with individual twins found associations in women between BMI and perceived stress (P=.01) and depression (P=.002), and the link between BMI and depression (P=.03) was significant in men. All physical health outcomes were significantly related to BMI. Once genetic and familial factors were taken into account, mental health outcomes were no longer significantly associated with BMI. BMI in women remained related to ratings of physical health (P=.01) and body pain (P=.004), independent of genetic and familial influences. CONCLUSION: These findings suggest that genetic and familial factors may account for the relationship between increased weight and poor mental health.
Comments

Citation: Schur E, Godfrey KM, Dansie E, Buchwald D, Pagoto S, Afari N. Can familial factors account for the association of body mass index with poor mental health in men or women? Gen Hosp Psychiatry. 2013 Sep-Oct;35(5):502-7. doi:10.1016/j.genhosppsych.2013.04.004.

Related Resources
Link to Article in PubMed
Keywords
  • Obesity,
  • Mental health,
  • Genetics,
  • Familial,
  • Body mass index
PubMed ID
23664570
Citation Information
Ellen Schur, Kathryn M. Godfrey, Elizabeth Dansie, Dedra Buchwald, et al.. "Can familial factors account for the association of body mass index with poor mental health in men or women" Vol. 35 Iss. 5 (2013) ISSN: 0163-8343 (Linking)
Available at: http://works.bepress.com/sherry_pagoto/98/