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Article
Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine
University of Massachusetts Medical School Faculty Publications
  • Tatsuyuki Yoshii, University of Massachusetts Amherst
  • Yingying Geng, University of Massachusetts Amherst
  • Shelly Peyton, University of Massachusetts Amherst
  • Arthur M. Mercurio, University of Massachusetts Medical School
  • Vincent M. Rotello, University of Massachusetts Amherst
UMMS Affiliation
Department of Molecular, Cell and Cancer Biology; UMass Metabolic Network
Date
9-1-2016
Document Type
Article
Disciplines
Abstract
Metastasis, drug resistance and recurrence in cancer are regulated by the tumor microenvironment. This review describes recent advances in understanding how cancer cells respond to extracellular environmental cues via integrins, how to build engineered microenvironments to study these interactions in vitro and how nanomaterials can be used to detect and target tumor microenvironments.
Rights and Permissions
Citation: Drug Discov Today. 2016 Sep;21(9):1489-94. doi: 10.1016/j.drudis.2016.05.011. Epub 2016 May 26. Link to article on publisher's site
Related Resources
Link to Article in PubMed
PubMed ID
27238384
Citation Information
Tatsuyuki Yoshii, Yingying Geng, Shelly Peyton, Arthur M. Mercurio, et al.. "Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine" Vol. 21 Iss. 9 (2016) ISSN: 1359-6446 (Linking)
Available at: http://works.bepress.com/shelly_peyton/1/