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Microwave-Assisted Preparation of Trifluoroacetaldehyde (Fluoral): Isolation and its Application
Tetrahedron Letters (2007)
  • Shainaz M. Landge, University of Massachusetts
  • Dmitry A. Borkin, University of Massachusetts
  • Béla Török, University of Massachusetts
A novel method for the preparation of trifluoroacetaldehyde (fluoral, TFAc, CF3CHO) from commercially available trifluoroacetaldehyde ethylhemiacetal (TFAE) by microwave irradiation is described. The isolation, characterization and reaction of fluoral with various nucleophiles were studied to verify the diverse applicability of this new method.
  • Trifluoroacetaldehyde,
  • Fluoral,
  • Microwave irradiation,
  • Trifluoromethylated alcohols
Publication Date
September 3, 2007
Publisher Statement
This is an Accepted Author Manuscript obtained from the PMC. The publisher's final edited version of this article is available at the Tetrahedron Letters.
Citation Information
Shainaz M. Landge, Dmitry A. Borkin and Béla Török. "Microwave-Assisted Preparation of Trifluoroacetaldehyde (Fluoral): Isolation and its Application" Tetrahedron Letters Vol. 48 Iss. 36 (2007) p. 6372 - 6376
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