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Article
A case of intramural pregnancy: the importance of differentiation from fibroid uterus
The Malaysian Journal of Pathology
  • S. A. Aziz, Aga Khan University
  • Shahid Pervez, Aga Khan University
  • S Khan, Aga Khan University
  • Naila Kayani, Aga Khan University
  • M H Rahbar, Aga Khan University
Publication Date
8-1-2001
Document Type
Article
Disciplines
Abstract
Breast cancer is an increasingly important cause of illness and death among women. In recent years several novel prognostic determinants of breast cancer have been identified which includes p53. Alterations of p53 are one of the most common abnormalities detected in primary breast cancer. In this study alteration of p53 in primary carcinoma breast was correlated with other pathological variables and disease outcome. In this prospective study the expression of p53 oncoprotein was analyzed immunohistochemically on 315 patient's tumour specimens of infiltrating ductal carcinoma of breast from 1992 to 1997. These patients also had axillary lymph nodes sampling. Both univariate and multivariate statistical analysis was performed to analyze results including disease outcome. Overexpression of p53 was observed in 55.23% tumours. Axillary lymph node metastasis had significant correlation with positivity of p53 (p
Citation Information
S. A. Aziz, Shahid Pervez, S Khan, Naila Kayani, et al.. "A case of intramural pregnancy: the importance of differentiation from fibroid uterus" The Malaysian Journal of Pathology Vol. 23 Iss. 2 (2001) p. 65 - 71
Available at: http://works.bepress.com/shahid_pervez/88/